3-Fluoropyridine-4-carboxylic acid mono hydrate

3-Fluoropyridine-4-carboxylic acid mono hydrate - Names and Identifiers

Name	3-Fluoropyridine-4-carboxylic acid
Synonyms	T6NJ BF CVQ [WLN] 3-Fluoroisonicotinic 3-FLUORONICOTINIC ACID 3-FLUOROISONICOTINIC ACID 3-Fluoroisonicotinic acid 3-Fluoro-4-pyridinecarboxylic 3-FLUORO-4-PYRIDINECARBOXYLIC ACID 3-FLUOROPYRIDINE-4-CARBOXYLIC ACID 3-Fluoropyridine-4-carboxylic acid 3-FLUOROISONICOTINIC ACID MONO HYDRATE 3-Fluoropyridine-4-carboxylic acid mono hydrate
CAS	393-53-3
EINECS	639-266-3
InChI	InChI=1/C6H4FNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H,9,10)
InChIKey	POLXLLIQWDBJMD-UHFFFAOYSA-N

3-Fluoropyridine-4-carboxylic acid mono hydrate - Physico-chemical Properties

Molecular Formula	C6H4FNO2
Molar Mass	141.1
Density	1.419±0.06 g/cm3(Predicted)
Melting Point	251-254°C (dec.)
Boling Point	360.0±22.0 °C(Predicted)
Flash Point	134.4°C
Vapor Presure	0.000559mmHg at 25°C
Appearance	White to Brown Solid
BRN	383678
pKa	2.85±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.541
MDL	MFCD03789251

3-Fluoropyridine-4-carboxylic acid mono hydrate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R10 - Flammable
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S16 - Keep away from sources of ignition.
WGK Germany	3
Hazard Class	IRRITANT

3-Fluoropyridine-4-carboxylic acid mono hydrate - Introduction

Acid, chemical formula C6H4FN02, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a colorless to light yellow solid.
-Melting point: about 120-125 ℃.
-Solubility: It is soluble in water, methanol, ethanol and dichloromethane and other solvents.

Use:
-must acid is a compound commonly used in organic synthesis, which can be used to synthesize pesticides, medicines and other organic compounds.
-It can also be used as an organic synthesis reagent, for example, a catalyst in catalyzing conjugate addition reactions.

Preparation Method:
-A common preparation method is to synthesize fluoracid by carboxylation of 3-fluoropyridine. The specific steps include the catalytic carboxylation reaction of 3-fluoropyridine with anhydrous ferric chloride and potassium carbonate in the presence of oxygen to finally obtain the target product.

Safety Information:
-the acid is generally a relatively safe compound under normal use conditions.
-But like other organic compounds, it can cause irritation to the skin, eyes and respiratory tract.
-During use and handling, it is recommended to wear appropriate personal protective equipment, such as gloves, safety glasses and masks.
-When preparing or using, it should be operated in a well-ventilated area.
-In the event of an accident such as contact or accidental ingestion, immediate medical assistance should be obtained and appropriate first aid measures should be taken according to the specific situation.

Last Update：2024-04-09 15:17:57